Riders have been drawn against CSO Voluntari of Romania in the first game of the Champions League Qualifying Rounds.
The game will be played on 21 September with the central venue being confirmed on 20 July.
Should Riders make it past CSO Voluntari, Rob Paternostro’s men then face TOFAŞ Spor Kulübü of Turkey.
The third knockout game would be against one of TFT Skopje (North Macedonia), Niners Chemnitz (Germany) or Fribourg Olympic (Switzerland).
Should the Riders reach the Champions League regular season they have been drawn in Group A alongside UCAM Murcia (Spain), Falco Szombathely (Hungary) and SIG Strasbourg (France).
Leicester Riders last competed in Europe in the 2018-19 season.